4.7 Article

G-quadruplex unfolding in higher-order DNA structures

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 82, Pages 9488-9490

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc44560g

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G-quadruplex unfolding within a sequence of two quadruplex units was characterized by gel electrophoresis, calorimetry and spectroscopy. The obtained results suggest that the kinetics and thermodynamics of the individual quadruplex unfolding are affected by its interaction with other DNA secondary structural elements.

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