Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 17, Pages 1741-1743Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc38939a
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Funding
- National Science Fund for Distinguished Young Scholars [21125522]
- 973 Program [2013CB733700]
- National Natural Science Foundation of China [91027035, 21105028]
- Science and Technology Commission of Shanghai Municipality Natural Science Foundation of Shanghai [11ZR1408900]
- Fundamental Research Funds for the Central Universities [WK1013002]
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SP1 protein as a new type of biological nanopore is described and is utilized to distinguish single-stranded DNA at the single-molecule level. Using the SP1 nanopore to investigate single molecule detection broadens the existing research areas of pore-forming biomaterials from unsymmetrical biological nanopores to symmetrical biological nanopores. This novel nanopore could provide a good candidate for single-molecule detection and characterization of biomaterial applications.
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