Click'' dendrimers as efficient nanoreactors in aqueous solvent: Pd nanoparticle stabilization for sub-ppm Pd catalysis of Suzuki-Miyaura reactions of aryl bromides

Palladium nanoparticles (PdNPs) with a size of 1.4 nm are stabilized by dendritic nanoreactors containing 1,2,3-triazole ligands with hydrophilic triethylene glycol (TEG) termini. These PdNPs are stable for months under air and are extremely active for the Suzuki-Miyaura reactions of aryl bromides down to sub-ppm levels.