Journal
JOURNAL OF COMBINATORIAL CHEMISTRY
Volume 2, Issue 5, Pages 513-521Publisher
AMER CHEMICAL SOC
DOI: 10.1021/cc000025u
Keywords
-
Ask authors/readers for more resources
The solid-phase synthesis of a 10 000 member combinatorial library of 1,5-benzodiazepine-2-one derivatives is reported. The 3-amino-1,5-benzodiazepine-2-one scaffold was prepared in solution, and the benzamide nitrogen was used as a point of attachment to the resin. The 5-aniline and 3-amine were then used as points of diversity. A 10 000 member library was synthesized using the Irori directed sorting system, and after analysis of a representative sample from the library, the Irori system was used to remove the compounds of lower purity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available