Journal
STEROIDS
Volume 65, Issue 9, Pages 529-535Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0039-128X(00)00131-8
Keywords
oxysterols; 7 alpha-hydroxyoxysterols; synthesis
Funding
- NHLBI NIH HHS [HL52069] Funding Source: Medline
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL052069] Funding Source: NIH RePORTER
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7 alpha-Hydroxy derivatives of oxysterols are of considerable interest because of their possible involvement in regulation of cholesterol metabolism This paper describes stereoselective syntheses and complete characterization of the 7 alpha-hydroxy derivatives of four key oxysterols: 25-hydroxycholesterol, 27-hydroxycholesterol, 24(S)-hydroxycholesterol, and 24(S),25-epoxycholesterol. (C) 2000 Elsevier Science Inc. All rights reserved.
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