4.7 Article

Application of chiral N-tert-butylsulfinyl vinyl aziridines in Rh(I) catalyzed 1,4-addition of aryl boronic acids to cyclic enones

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 57, Pages 6433-6435

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc42673d

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Funding

  1. Natural Science Foundation of China (NSFC) [20902015]
  2. Fundamental Research Funds for the Central Universities [HIT.NSRIF.2010055, HIT.BRETIV.201310]
  3. SKLUWRE [2010QN06]

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Chiral N-tert-butylsulfinyl vinyl aziridine ligands prepared from a readily available (R)-tert-butanesulfinamide have been applied in the rhodium-catalyzed asymmetric 1,4-addition of aryl boronic acids to cyclic enones, which gives high yields and excellent enantioselectivities.

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