4.7 Article

Fluorescent water-soluble perylenediimide-cored cationic dendrimers: synthesis, optical properties, and cell uptake

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 35, Pages 3646-3648

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc40330k

Keywords

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Funding

  1. National Science Foundation of China [21174012, 51103008, 51221002]
  2. Special Fund for Agro-scientific Research in the Public Interest [201003025]
  3. 973 Program [2013CB127603]
  4. Ministry of Education of China [NCET-10-0215, 09-0734]
  5. Doctoral Program of Higher Education Research Fund [20100010120006, 20120010110008]

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Different generations of perylenediimide-cored dendrimers with peripheral amine groups were synthesized. All these water-soluble dendrimers could rapidly internalize into live cells with high efficacy of gene transfection and low cytotoxicity. Increasing dendrimer generation increased their ability for gene transfection.

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