4.7 Article

Molecularly-imprinted nanoparticles that recognize Naja mossambica cytotoxins: binding studies and biological effects

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 53, Pages 5954-5956

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc42394h

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We report the development of molecularly imprinted polyacrylamide nanoparticles that bind to and neutralize the activity of cytotoxins present in the venom of the Mozambique Spitting Cobra (Naja mossambica mossambica). The binding activity of these nanoparticles is avid and specific. These findings hold promise for the development of a synthetic antivenom.

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