Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 14, Pages 1392-1394Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc37438b
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Funding
- Natural Sciences and Engineering Research Council of Canada
- 20/20: NSERC Ophthalmic Materials Network
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A new class of surface-active compounds based on the combination of silicones and boronic acids is described. The properties of the compounds can be tuned by manipulation of both the hydrophobic (silicone size and 3D structure) and hydrophilic components (by binding different saccharides to the boronic acid). Stabilization of the four-coordinate boron structure is provided by Tris buffer that also maintains neutral pH to suppress silicone hydrolysis.
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