Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 50, Pages 5687-5689Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc42588f
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Funding
- National Science Foundation [NSF 21072080, 21272101]
- National Basic Research Program of China (973 Program) [2010CB833203]
- 111 program of MOE
- [PCSIRT: IRT1138]
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A mild and efficient copper-catalyzed trifluoromethylation reaction which involves the cyclization of oximes has been developed. This method provides a convenient access to a variety of useful CF3-containing 4,5-dihydroisoxazoles by constructing a C-CF3 bond and a C-O bond in one step.
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