4.7 Article

Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 52, Pages 6502-6504

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc32147e

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Funding

  1. European Research Council
  2. Trinity College Dublin

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A new, highly enantio- and diastereoselective catalytic asymmetric formal cycloaddition of aryl succinic anhydrides and aldehydes which generates paraconic acid (gamma-butyrolactone) derivatives is reported.

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