4.7 Article

A facile route to flavone and neoflavone backbones via a regioselective palladium catalyzed oxidative Heck reaction

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 24, Pages 2985-2987

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc18150a

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Funding

  1. Iran National Science Foundation (INSF)
  2. University of Tehran

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A straightforward and atom-economical base-free palladium-catalyzed regioselective direct arylation of coumarins and chromenones is devised. This protocol is compatible with a wide variety of electron-donating and -withdrawing substituents and allows construction of various biologically important flavone and neoflavone backbones.

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