Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 6, Pages 916-918Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc16432e
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Funding
- University of South Carolina
- USDA NIFA [2011-51160-31205]
- State Forestry Administration of China [200804011]
- Research Institute of New Technology of Chinese Academy of Forestry [CAFINT2010C05, CAFYBB2010003]
- NIFA [2011-51160-31205, 579477] Funding Source: Federal RePORTER
- Division Of Materials Research
- Direct For Mathematical & Physical Scien [1206072] Funding Source: National Science Foundation
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We report novel robust resin acid-derived antimicrobial agents that exhibit excellent antimicrobial activities against a broad spectrum of bacteria (6 Gram-positive and 7 Gram-negative) with selective lysis of microbial membranes over mammalian membranes. Our results indicate that hydrophobicity and unique structures of resin acids can be determining factors in dictating the antimicrobial activity.
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