Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 80, Pages 10043-10045Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc34217k
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Funding
- CAREER award [NSF/CBET-0846274]
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Fractalkine (FKN) is a unique cell surface protein with potential as a therapeutic target because of its role in inflammatory diseases and cancer. We developed an aptamer, named FKN-S2, with a dissociation constant of 3.4 +/- 0.7 nM that is specific to the chemokine domain of fractalkine.
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