Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 55, Pages 6906-6908Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc31023f
Keywords
-
Categories
Ask authors/readers for more resources
The di-copper(II) cation, [Cu-2(mu-terephthalate)(1,10-phen)(4)](2+), is a powerful, non-sequence-specific, minor-groove oxidizer of duplex DNA which, unlike copper(II) bis-1,10-phenanthroline chloride, operates independently of exogenous reagents. The agent displays excellent in vitro cytoxicity towards cisplatin-resistant ovarian cancer cells, producing intracellular reactive oxygen species upon nano-molar exposure.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available