4.7 Article

Water-dispersible and biodegradable polymer micelles with good antibacterial efficacy

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 54, Pages 6857-6859

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc31529g

Keywords

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Funding

  1. NSFC [21174107, 21074095]
  2. PhD program foundation of MOE [20110072110048]
  3. MOE [NCET-10-0627]
  4. fundamental research funds for the central universities, Pujiang project [10PJ1409900]
  5. CXY
  6. Shanghai education commission [11CXY16, 11ZZ31]
  7. Eastern Scholar program
  8. Shanghai 1000 Plan

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New amphiphilic ABC triblock copolymers have been designed and self-assembled into water-dispersible and biodegradable polymer micelles, which exhibit good antibacterial activities without quaternary ammonium moieties or the loading of any external antibiotics due to the increased local concentration of cationic charge in the polymer micelles compared to the un-self-assembled individual polymer chains.

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