4.7 Article

Fluorescence quenching of gold nanoparticles integrating with a conformation-switched hairpin oligonucleotide probe for microRNA detection

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 87, Pages 10718-10720

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc35564g

Keywords

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Funding

  1. NSFC [21175067, 21273117]
  2. NSF of Jiangsu Province [BK2011779]
  3. Foundation of the Jiangsu Education Committee [09KJA150001, 10KJB150009]
  4. Program for Outstanding Innovation Research Team of Universities in Jiangsu Province
  5. Priority Academic Program Development of Jiangsu Higher Education Institutions

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We report a new strategy for microRNA analysis based on the fluorescence quenching of gold nanoparticles (AuNPs) integrating with a conformation-switched hairpin-structured oligonucleotide probe for improving selectivity.

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