4.7 Article

A label-free electrochemical assay for quantification of gene-specific methylation in a nucleic acid sequence

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 12, Pages 1769-1771

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc15398j

Keywords

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Funding

  1. National Natural Science Foundation of China [21175158, 20975117, 81171666]
  2. Scientific Technology Project of Guangdong Province [2010A040302001, 2011B031800257]
  3. Natural Science Foundation of Guangdong Province [10151027501000070]
  4. The PhD Programs Foundation of the Ministry of Education of China [20110171110014]

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A label-free electrochemical method is developed for simple and convenient quantification of gene-specific DNA hypermethylation in a DNA sequence without PCR amplification, bisulfite conversion or labeling processes.

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