4.7 Article

Photoinduced in situ generation of a DNA-binding benzothiazoloquinolinium derivative

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 38, Pages 4603-4605

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc30958k

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Funding

  1. Deutsche Akademische Austauschdienst [A/10/85281]

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A styrylbenzothiazole substrate that has no significant affinity towards DNA was transformed photochemically into a DNA-binding benzothiazoloquinolinium ion. The photoreaction may be performed directly in the presence of DNA thus establishing the DNA-ligand interaction in situ with temporal control.

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