4.1 Article

HMG-box sequences from microbats homologous to the human SOX30 HMG-box

Journal

GENETICA
Volume 110, Issue 2, Pages 157-162

Publisher

SPRINGER
DOI: 10.1023/A:1017914005677

Keywords

HMG-box; microbats; SOX; SOX30

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SOX genes are a family of genes that encode for proteins which are characterised by the presence of a HMG-domain related to that of the mammalian sex-determining gene (SRY). By definition, the DNA binding domain of SOX genes is at least 50% identical to the 79 amino acid HMG domain of the SRY gene. We report here two HMG-box sequences from two microbat species (R. ferrumequinum and P. Pipistrellus) which were PCR amplified using a primer pair specific to the mouse Sry HMG-box. The high percentage of identity of this sequences with the human and mouse SOX30 HMG-box suggests that they are the SOX30 HMG-box for these two bat species.

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