Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 2, Pages 194-196Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc15412e
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Funding
- National Basic Research Program of China [2010CB732402]
- NSFC [20805038, 21075104]
- MOE [200803841013]
- Natural Science Foundation of Fujian Province for Distinguished Young Scholars [2010 J06004]
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Based on graphene oxide-protected DNA probes, we have developed a cyclic enzymatic amplification method for sensitive miRNA detection in complex biological samples. By using the quenching nature of graphene oxide for multiple fluorophores, this method can distinguish highly similar miRNA sequences and detect them simultaneously.
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