4.7 Article

Colorimetric logic gates based on aptamer-crosslinked hydrogels

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 9, Pages 1248-1250

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc15639j

Keywords

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Funding

  1. Shanghai [11XD1401900, 09JC1404100]
  2. Fundamental Research Funds for the Central Universities
  3. National Institutes of Health [GM066137, GM079359, CA133086]
  4. [NSF21075040]
  5. NATIONAL CANCER INSTITUTE [R01CA133086] Funding Source: NIH RePORTER
  6. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM066137, R01GM079359] Funding Source: NIH RePORTER

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We have developed a novel molecular logic gate system based on the incorporation of aptamer-crosslinked hydrogels. Modified gold nanoparticles are used as the output signal, which is visible to the naked eye. This system is designed for AND and OR operations using two chemicals as stimulus inputs.

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