Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 65, Pages 8105-8107Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc33768a
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Funding
- National Natural Science Foundation of China [NSFC-21002077]
- Fund of New Scientific Stars of Shanxi Province [2012KJXX-26]
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A novel and general procedure for Cu-catalyzed coupling of enamides with alkynes to synthesize substituted pyridines was developed. The chemistry was allowed to extend to the synthesis of substituted isoquinolines by coupling of enamides with arynes under transition-metal-free conditions.
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