Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 17, Pages 2343-2345Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc16637b
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Funding
- National Science Foundation (NSF) [21072080]
- National Basic Research Program of China (973 Program) [2010CB833203]
- MOE
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Highly substituted 2-aminated indoles can be prepared in moderate to excellent yields by regioselective C2-amination of indoles promoted by iodine. As a key step in a concise synthesis of (+/-)-folicanthine, its core structure was easily obtained by one step cyclization-dimerization of substituted tryptophan in high yield on a gram scale.
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