Journal
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY
Volume 38, Issue 6, Pages 625-630Publisher
MARCEL DEKKER INC
DOI: 10.1081/CLT-100102011
Keywords
-
Categories
Ask authors/readers for more resources
Introduction: Methylphenidate is prescribed commonly for children with attention deficit hyperactivity disorder. An estimated 2.8% of US youths aged 5 to 18 years use it for the management of this disorder, Despite the widespread use of methylphenidate, the demographics and outcome of intentional and unintentional exposures to methylphenidate have not been described. Methods: To profile human exposures to methylphenidate, a retrospective review of all reports to a certified regional poison information center during 1998 was conducted. Data analysis included patient demographics, reason for the exposure, dose ingested, clinical effects, and patient outcome. Results: There were 113 methylphenidate human exposures. The following table summarizes the values for selected parameters that were investigated: [GRAPHICS] Conclusions: The majority of exposures in children less than or equal to 12 years of age involved unintentional ingestion of a sibling's medication, self-administration of an excessive therapeutic dose, or the administration of an inadvertent dose given by a caregiver. Methylphenidate abuse was common among adolescents and adults. Regardless of the reason for the exposure, the amount ingested, or treatment, all exposures had a favorable outcome. Pediatric doses of less than 1 mg/kg were not associated with adverse events.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available