Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 23, Pages 2903-2905Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc18001d
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Funding
- National Natural Science Foundation of China [21032007, 21172038]
- Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science AMP
- Technology Normal University
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A novel and efficient route for the preparation of quinazolin-4(3H)-imines via a palladium-catalyzed three-component reaction of carbodiimide, isocyanide, and nucleophile is described. The palladium-catalyzed isocyanide insertion is believed to be the key step during the reaction process.
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