4.7 Article

A lateral flow biosensor for detection of nucleic acids with high sensitivity and selectivity

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 2, Pages 236-238

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc15878c

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Funding

  1. Foundation of Special Research of Science and Technology Bureau of Guangzhou [2008Z1-E581, 2009Ss-P030]
  2. Chinese Academy of Science [KSCX2-YW-R-164]
  3. Department of Education of Guangdong Province [GXZD0901]

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A lateral flow biosensor based on isothermal strand-displacement polymerase reaction and gold nanoparticles has been developed for the visual detection of nucleic acids with a detection limit of 0.01 fM.

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