Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 50, Pages 6253-6255Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc32227g
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A robust, modular fluorogenic probe system has been developed which allows the highly sensitive off-ON detection of aminopeptidase activity by releasing an exceptionally photostable, insoluble, phenolic ESIPT fluorophore. The probes generate no false positive signal in over 24 hours, but when activated give a signal within 10 minutes.
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