Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 81, Pages 10132-10134Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc35283d
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Funding
- BRNS, DAE, India
- CSIR, New Delhi
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A Lewis acid catalyzed Friedel-Crafts reaction of electron rich aromatics with 3-alkyl-3-hydroxy-2-oxindole (5) has been developed. The methodology provides a straightforward access to the core of azonazine (2) sharing an all-carbon quaternary stereocenter at the tetracyclic ring junction.
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