Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 7, Pages 1018-1020Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc16684k
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Funding
- National Natural Science Foundation of China [21105052]
- Natural Science Foundation of Shandong province [ZR2011BQ025]
- Educational Administration Foundation of Shandong Province [J11LB04]
- National Basic Research Program of China [2010CB732404]
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The network consisting of three kinds of unlabeled stem-loop DNA molecular beacons (MBs) is activated by target DNA in the presence of exonuclease-III (Exo-III), achieving the concept of exonuclease-assisted cascaded recycling amplification (Exo-CRA) for DNA detection with a wide dynamic range of 8 orders of magnitude.
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