4.7 Article

Folding super-sized DNA origami with scaffold strands from long-range PCR

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 51, Pages 6405-6407

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc32204h

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Funding

  1. National Natural Science Foundation [21105110, 21103219]

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A 26 kilobase single strand DNA fragment was obtained from long-range PCR amplification and subsequent enzymatic digestion, which we folded into a super-sized DNA origami nanostructure by using similar to 800 staple strands.

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