4.7 Article

A dramatic concentration effect on the stereoselectivity of N-glycosylation for the synthesis of 2′-deoxy-β-ribonucleosides

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 56, Pages 7097-7099

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc33155a

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Funding

  1. Ministry of Science and Technology of China [2012ZX09502-002]
  2. National Natural Science Foundation of China [20932009, 20921091]

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A dramatic concentration effect on the stereoselectivity of N-glycosylation, which is attributable to a low-concentration-facilitated remote-participation, has been disclosed, leading to convenient synthesis of the 2'-deoxy-beta-ribonucleosides of biological significance.

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