4.7 Article

Cobalt-catalyzed arylation of aldimines via directed C-H bond functionalization: addition of 2-arylpyridines and self-coupling of aromatic aldimines

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 36, Pages 4305-4307

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc31114c

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Funding

  1. Singapore National Research Foundation [NRF-RF-2009-05]
  2. Nanyang Technological University
  3. JST, CREST

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A cobalt-N-heterocyclic carbene catalyst, in combination with an appropriate Grignard reagent, promotes a chelation-assisted aromatic C-H functionalization reaction via addition to an aromatic aldimine.

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