4.7 Article

Homogeneous electrochemical monitoring of exonuclease III activity and its application to nucleic acid testing by target recycling

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 70, Pages 8772-8774

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc34511k

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Funding

  1. Fundacion Ramon Areces

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A simple and fast electrochemical nucleic acid assay based on a target recycling strategy and the release of a double-stranded DNA intercalating redox probe upon digestion of a specific duplex by exonuclease III is demonstrated.

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