4.7 Article

Nanoplasmonic detection of adenosine triphosphate by aptamer regulated self-catalytic growth of single gold nanoparticles

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 77, Pages 9574-9576

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc34632j

Keywords

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Funding

  1. National Science Fund for Distinguished Young Scholars [21125522]
  2. National Natural Science Foundation of China [91027035, 21105028, 0873175, 21075128]
  3. 973 program [2012CB932600]
  4. Fundamental Research Funds for the Central Universities [WK1013002]

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We present a nanoplasmonic aptasensor for adenosine triphosphate (ATP) by using single gold nanoparticles (GNPs) as probes. The specific aptamer-ATP binding induced conformational change could modulate the surface-dependent self-catalytic growth of GNPs, which enabled the detection of ATP with ultra-sensitivity and selectivity.

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