4.7 Article

Ferric chloride-catalyzed C-N bond cleavage for the cyclization of arylallenes leading to polysubstituted indenes

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 88, Pages 10913-10915

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc36048a

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Funding

  1. National Natural Science Foundation of China [21172206, 20972147]
  2. National Basic Research Program of China (973 Program) [2010CB833300]
  3. Program for Changjiang Scholars and Innovative Research Team in University [IRT1189]

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A range of arylallenes undergo carbocation-initiated cyclization reaction with N-benzylic and N-allylic sulfonamides in the presence of 10 mol% ferric chloride to give structurally diverse polysubstituted indenes in good yields with extremely high regioselectivity.

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