4.7 Article

Dual polarisation interferometry for real-time, label-free detection of interaction of mercury(II) with mercury-specific oligonucleotides

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 23, Pages 2873-2875

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc16279b

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Funding

  1. National Natural Science Foundation of China [21175124, 20890022]
  2. National Key Basic Research Development Project of China [2010CB933602]

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A real-time, label-free dual polarisation interferometry technique was used to investigate the interaction of Hg2+ with a 21-mer T-rich oligonucleotide and further construct a Hg2+ biosensor based on thymine-Hg2+ -thymine coordination chemistry.

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