Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 6, Pages 808-810Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc15913e
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Funding
- NSFC [20928001, 21072163, 21002083, 21102124]
- Sci. Foundation in Interdisciplinary Major Res. Project of XZNU [09XKXK01]
- PADA of Jiangsu Higher Education Institutions
- Robert A. Welch Foundation [D-1361]
- NIH [R21DA031860-01]
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A novel multi-component reaction for the synthesis of polyfunctionalized indoles and bis-indoles has been established. The reaction pathways were controlled by varying enamines with different substitution patterns to give polyfunctionalized indoles and bis-indoles selectively. The reaction proceeds at a fast speed within 15-30 min with water as the major byproduct, which makes work-up convenient.
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