4.7 Article

A low-molecular-weight supramolecular hydrogel of riboflavin bolaamphiphile for VEGF-siRNA delivery

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 71, Pages 8901-8903

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc34466a

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Funding

  1. EPB Centre [2012-0000534]
  2. WCU Programme [R31-10105]

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A low-molecular-weight hydrogel derived from riboflavin (vitamin B-2) that self-assembles to provide supramolecular nanofibers, biocompatible material, can be used to deliver VEGF-siRNA efficiently into human cells by the endocytosis pathway, where the siRNA is functionalized.

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