4.7 Article

Fluorescence sensing of spermine with a frustrated amphiphile

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 47, Pages 5841-5843

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc32228e

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Funding

  1. Swiss National Science Foundation
  2. EPFL

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A charge-frustrated amphiphile composed of a pyrene-1,3,6-trisulfonate head group and an eicosane side chain can be used as a fluorescence chemosensor for spermine. The sensor allows the detection of spermine down to the nanomolar concentration range with good selectivity over closely related biogenic amines such as spermidine.

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