Journal
NEUROLOGICAL SCIENCES
Volume 21, Issue 5, Pages S981-S982Publisher
SPRINGER-VERLAG
DOI: 10.1007/s100720070015
Keywords
MELAS; idebenone; ribonavin; therapy
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We report a patient with MELAS treated for 24 months with idebenone and riboflavin, during which no stroke-like episodes occurred. Moreover neurological symptoms clearly improved, and a recovery of brain MRI and EEG abnormalities was observed. We conclude that the combined treatment with idebenone and riboflavin may restore the metabolic impairment in MELAS, possibly improving the long-term prognosis in these patients.
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