Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 24, Pages 2991-2993Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc17093k
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Funding
- MICINN of Spain [CTQ2006-01123, CTQ2007-68014-C02-02, CTQ2009-13705, BFU2007-63287]
- Generalitat de Catalunya [2009/SGR/208]
- Instituto de Salud Carlos III (CIBER-BNN) [CB06_01_0019]
- CSIC
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Mono- and disaccharides have been shown to stack on top of DNA duplexes stabilizing sequences with terminal C-G base pairs. Here we present an apolar version of glucose and cellobiose as new capping agents that stack on DNA increasing considerably its stability with respect to their natural polyhydroxylated mono- and disaccharide DNA conjugates.
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