4.7 Article

Immobilization-free screening of aptamers assisted by graphene oxide

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 15, Pages 2071-2073

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc16473f

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Funding

  1. National Research Foundation of Korea (NRF)
  2. Korea government (MEST) [2010-00579-KORANET]
  3. Small & Medium Business Administration (SMBA) [S1071611]

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Graphene oxide (GO) has the ability to separate free short ssDNA in heterogeneous solution. This feature is applied as a label free platform for screening of aptamers that bind to their target with high affinity and specificity. Herein, we report an aptamer selection strategy for Nampt protein based on GO.

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