3.8 Review

The effects of mechanical forces on lung functions

Journal

RESPIRATION PHYSIOLOGY
Volume 119, Issue 1, Pages 1-17

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/S0034-5687(99)00092-4

Keywords

forces, mechanical, lung, cell types; lung function, mechanical lung forces; mechanics of breathing, lung function

Funding

  1. NHLBI NIH HHS [PPG HL 24075] Funding Source: Medline
  2. PHS HHS [R01 57426] Funding Source: Medline
  3. NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [P01HL024075] Funding Source: NIH RePORTER

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The lung is a dynamic organ that is subjected to mechanical forces throughout development and adult life. This review article addresses the types of mechanical forces in the lung and their effects on development and normal lung functions. The effects of mechanical forces on the various different cell types of the lung are discussed, as are the mechanisms underlying mechanotransduction. (C) 2000 Elsevier Science B.V. All rights reserved.

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