4.7 Article

A facile approach for sensitive, reversible and ratiometric detection of biothiols based on thymine-mediated excimer-monomer transformation

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 48, Pages 6007-6009

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc32064a

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Funding

  1. NSFC [21025415, 21174040, 50973032]

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A ratiometric fluorescent sensor was developed for detecting biothiols in water and biological samples such as urine and serum. For this sensor, the monomer-excimer emission variations were regulated by aggregation and deaggregation via the complexation between pyrene-thymine and mercury ions modulated by biothiols.

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