☆ 4.7 Article

Ratiometric fluorescence imaging for distinguishing chloride concentration between normal and ischemic ventricular myocytes

CHEMICAL COMMUNICATIONS (2012)

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Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 15, Pages 2077-2079

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc15258k

Keywords

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Categories

Chemistry, Multidisciplinary

Funding

  1. National Natural Science Funds for Distinguished Young Scholar [20725518]
  2. National Key Natural Science Foundation of China [21035003]
  3. Science and Technology Development Programs of Shandong Province of China [2008GG30003012, 2010G0020243]
  4. Key Natural Science Foundation of Shandong Province of China [ZR2010BZ001]
  5. Program for Changjiang Scholars and Innovative Research Team in University
  6. National Natural Science Foundation of China [20975063]

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We devised a new ratiometric fluorescent probe for the detection of chloride ions. This synthesized probe was applied to the ventricular myocytes to successfully realize dynamic imaging of Cl- concentration fluctuations during the myocardial ischemia course.

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