4.7 Article

A general stereoselective enamine mediated alkylation of alpha-substituted aldehydes

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 30, Pages 3614-3616

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc17482k

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Funding

  1. PRIN (Progetto Nazionale Stereoselezioni in Chimica Organica: Metodologie ed Applicazioni)
  2. Bologna University
  3. Fondazione Del Monte
  4. European Commission [FP7-201431]

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We herein present a general enamine-mediated alpha-alkylation of alpha-substituted aldehydes with carbenium ions for the stereoselective construction of quaternary stereogenic centers.

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