4.7 Article

Cisplatin-encapsulated organic nanotubes by endo-complexation in the hollow cylinder

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 69, Pages 8625-8627

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc33970f

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A bipolar glycolipid self-assembles into organic nanotubes upon its chelation with an anticancer drug cis-dichlorodiamineplatinum(II) (CDDP). The facile synthesis of glycolipid, chelation-assisted formation of the nanotubes, and efficient loading and prolonged release of CDDP demonstrate a new approach to high-axial supramolecular drug nanocarriers.

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