Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 40, Pages 4899-4901Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc31001e
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Funding
- National Natural Science Foundation of China [21172206, 20972147]
- National Basic Research Program of China (973 Program) [2010CB833300]
- Program for Changjiang Scholars and Innovative Research Team in University [IRT1189]
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A range of 3H-indoles and 2H-benzo[b][1,4]thiazines smoothly undergo asymmetric Strecker reaction with ethyl cyanoformate in the presence of a Cinchona alkaloid-based thiourea catalyst at 10 degrees C to give structurally diverse nitrogen-containing heterocycles in good to excellent yields and with excellent ee.
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