4.7 Article

One-step synthesis of novel glycosyltransferase inhibitors

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 97, Pages 11856-11858

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc36798j

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Funding

  1. KCL Futures Fund
  2. MRC [0901746]
  3. Medical Research Council [G0901746] Funding Source: researchfish
  4. MRC [G0901746] Funding Source: UKRI

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A one-step synthesis of two 5-CF3 UDP-sugars is reported. These non-natural sugar-nucleotides are micromolar inhibitors of two different galactosyltransferases.

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